By Martin Stefan, Mike Travis, Robin Murray
Written by means of a crew of specialists operating on the vanguard of this box, An Atlas of Schizophrenia describes schizophrenia's profound results on conception, figuring out, conversation, and social habit; its identifiable antecedents in early mind progress and improvement; and its morphological information from structural mind imaging and autopsy reviews. It covers, with examples, the most recent study advancements in neuropsychology, psychophysiology, and useful imaging in addition to in vivo receptor imaging and different advances in psychopharmacology which are laying off new mild at the neurochemistry of schizophrenia.Diagrams, tables, and figures bought via smooth imaging suggestions mixed with examples of work from the Bethlem Royal health facility information and Museum illustrate the human in addition to the medical and psychiatric features of the disease. those gains offer you an entire photo of schizophrenia, its prognosis, and administration. With its mixture of the most recent examine and scientific information and state of the art mind imaging options, An Atlas of Schizophrenia offers a special visible presentation of the present knowing of the medical positive aspects, etiology, pathophysiology, and healing procedures to be had.
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Extra resources for Atlas of Schizophrenia, Second Edition
The phenothiazines include chlorpromazine, trifluoperazine and fluphenazine. g. g. 1). The newer ‘atypical’ antipsychotics are mostly in different chemical classes, although they may share pharmacological characteristics. NEUROCHEMISTRY OF SCHIZOPHRENIA AND MECHANISMS OF ACTION OF ANTIPSYCHOTICS Dopamine The observation from the early use of chlorpromazine that clinical improvement was often accompanied by a parkinsonism-like syndrome led ©2002 CRC Press LLC to a focus on dopaminergic mechanisms of action for antipsychotics.
Extracerebral markers of abnormal fetal development provide indirect support for the idea that aberrant neurodevelopment is implicated in schizophrenia. 8). 6 Agenesis of the corpus callosum. This midline sagittal magnetic resonance image shows an absent corpus callosum, a dramatic example of a neurodevelopmental anomaly which, while extremely rare, is thought to have an increased incidence in people with schizophrenia schizophrenic patients compared with normal controls. 9)5. It was previously thought that a decrease in frontal blood flow and metabolism (‘hypofrontality’) was a constant feature of schizophrenia.
A meta-analysis of studies of the ventricle : brain ration (VBR). Br J Psychiatry 1992;160:687–97 Suddath RL, Christison GW, Torrey EF, et al. Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. N Engl J Med 1990;322:789–34 Wright IC, Rabe-Hesketh S, Woodruff PW, et al. Meta-analysis of regional brain volumes in schizophrenia. Am J Psychiatry 2000;157:16–25 Akbarian S, Bunney WE, Jr, Potkin SG, et al. Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development.
Atlas of Schizophrenia, Second Edition by Martin Stefan, Mike Travis, Robin Murray